Something to do is to go out in Casco! For a comprehensive list of gay and lesbian-friendly hotels, check out Purple Roofs and World Rainbow Hotels. A proposal that would have allowed same-sex civil unions was defeated inmainly due to pressure on the Government from the Roman Catholic Church. It's not San Fransisco or anything - we're still talking Latin America, so while they are accepted, gays are still often the object of humor and jokes on TV as well as in person. Load More… Follow on Instagram.
Panama is a very Catholic country.
Unlike on Airbnb, you know your host is gay, avoiding any nasty surprises when you check in. In Maya year-old Panamanian transgender woman was allowed to change her name, so that it matches her gender identity, without having undergone surgery. Sincetransgender persons in Panama can change their legal gender and name on their birth certificates, but only after having undergone sex reassignment surgery.
Maybe take a more discreet approach if traveling into the more rural locations outside the big city.